Waddell Medical Research Institute
Study brief template

Working title
Study lead and contributors
Date and version
Study type
Funding and conflicts of interest

1. Research question
State what you expect to learn. Describe the population or model, exposure or
intervention, comparator, and outcome where applicable.

2. Evidence and data
List the sources, persistent identifiers, access terms, and source versions.
For a literature review, record databases, search dates, search terms, and
inclusion and exclusion rules. Document permissions or review requirements
that apply to the work. Keep patient-identifiable information out of this brief.

3. Methods and outcomes
Describe the design, primary outcome, comparison, and analysis plan. State how
you will handle missing data, bias, and uncertainty. For an empirical study,
record sample-size reasoning and stopping rules where applicable. Identify
measured observations, simulated or modeled outputs, and hypotheses explicitly.

4. Review and registration
List the methods expertise needed and potential reviewer conflicts. Record
applicable ethics or data-access determinations and the registration link when
available. Log deviations from the original plan with dates and reasons.

5. Outputs and reproducibility
List the planned evidence tables, data or code that can be shared, publication
venue, and method for reporting corrections. Document any limits on reuse.

Submit a shareable version for peer review at
https://waddell-medical-research.nukaknight3621.chatgpt.site/submit